Zhu Ling grows under the ground on rotting wood. It stays fresh in wet soils for over a year, which proves that it has a powerful immune system loaded with chemical compounds to fight off microbes.
In confirmation of its use in Traditional Chinese Medicine (TCM) for urogenital infections, one study showed Zhu Ling having an inhibitory effect on Chlamydia trachomatis. [302]
Other modern studies have found Zhu Ling useful against parasites, hepatitis B and for strengthening the immune system. [303, 304] It’s also been reported to have an effect on certain types of cancer in conjunction with standard cancer treatment, [305, 306, 307, 308] including bladder and liver cancer, [309] as well as leukemia. [310, 311] Used as an adjunct to chemotherapy and radiation, it appears to help speed up immune system recovery. [312] Two papers published in 1991 and 1994 also presented findings that Zhu Ling administered after chemotherapy and radiation helped lower cancer recurrence rates by 68% and 50% respectively. [313, 314]
In terms of its anti-parasitic effects, lab tests have shown Zhu Ling to be 100% effective against both Brucella spp. (brucellosis) and Plasmodium falciparum (malaria). [310] However, it has not yet to our knowledge been tested on live patients afflicted with malaria.
Tests on live subjects with brucellosis have been conducted, showing an improvement in immune system function. [315, 316] Immune system suppression is a characteristic symptom of brucellosis.
As previously mentioned, another of the many uses of Zhu Ling in Traditional Chinese Medicine is for hepatitis B. This use has been affirmed by modern research. [317, 318] A 2001 study reported that although not powerful enough as a standalone treatment of hepatitis B, it was useful in combination with other treatments. [319, 320] Positive results have also been reported in use of Zhu Ling with toxic hepatitis. [321]
A recent study conducted in 2008 showed Zhu Ling extract exhibiting potent anti-inflammatory properties. [322]
As a diuretic, a modern study reported that Zhu Ling did indeed help increase low urine production. However, it simultaneously decreased urine production in patients with already excessive urine output. [301]
A logical conclusion from this is that Zhu Ling could be conveniently given to patients waiting to provide a urine sample in order to expedite the process. [300]
Medicinal mushroom expert Paul Stamets (Mycelium Running) also lists lung conditions and viruses as areas of therapeutic use for Zhu Ling. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any herb (or mushroom) except as advised by a licensed medical practitioner.
Credit to Paul Stamets for research and source material.
Dr. Rafael has worked with natural health since finishing Chiropractic College in the mid-90′s. His current focus is medicinal fungi, specifically working with the extracts of Paul Stamets’ Fungi Perfecti. (Paul Stamets includes Zhu Ling in his Stamets 7 Blend.) For scientific article references, please go to Zhu Ling Mushroom page. Click on number indicating reference.

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